Breast Cancer

Breast Cancer Awareness - 12 Things You Should Know

Tuesday, October 27th, 2009

breast_cancer_awareness_mothIt’s Breast Cancer Awareness Month, and here’s an article from delmarvanow.com that has 12 things you should know about the disease.

1. Clinical breast exams are as important as mammograms. Mammograms starting at age 40 are crucial (get them earlier if you have a family history of the disease), but they’re an imperfect screening tool, especially in women who have dense breasts. That’s why an annual clinical breast exam from a doctor is a must.

2. Don’t panic if you get called for a mammogram “redo” or have calcifications. Many women over 40 have calcium deposits (calcifications) in their breasts, and most of them are benign.

3. Get your folate. While experts say that an overall healthy diet may help prevent breast cancer, a growing body of research suggests that getting enough of the B vitamin folate (in leafy green vegetables, beans and fortified cereals) may help mitigate the increased risk associated with drinking alcohol.

4. Being overweight is riskiest after menopause. “In postmenopausal women, one of the most significant sources of estrogen comes from body fat,” explained Dr. Isaacs. “So if you’re overweight, you have higher amounts of circulating estrogen, which could stimulate breast cancer growth.” And it doesn’t take much: Losing even 10 pounds may help lower your risk.

5. Active women are less likely to develop and die from breast cancer. Regular exercise has consistently been associated with a lower risk of breast cancer. “Any type of exercise is likely to help by lowering estrogen levels,” Dr. Seewaldt explained.

6. Steer clear of soy supplements. Soy contains isoflavones, which can act like estrogen in your body and potentially stimulate the growth of certain types of breast cancer, explained Seema A. Khan, M.D., a professor of surgery and co-leader of the breast cancer program at Northwestern University in Chicago. But soy foods — edamame, soy milk, tofu — are fine.

7. Lumpy breasts don’t mean a higher risk of cancer. Many women have cysts in their breasts that come and go throughout their menstrual cycles (which are also known as fibrocystic changes). Feeling any kind of lump or bump can be scary, but these types of cysts don’t typically lead to cancer, Dr. Seewaldt points out. Pain also isn’t usually a sign of breast cancer. If you have pain in one or both breasts, rest assured: It’s probably due to hormonal changes, a benign cyst, a ligament strain or another condition, said Dr. Isaacs.

8. Breast cancer risk is not 1 in 8 for all women. That stat applies to lifetime risk, assuming you live to 85 or beyond. At age 40, the average woman has a 1 in 69 chance of getting breast cancer in the next 10 years; at 50, the risk rises to 1 in 42; at 60, it’s 1 in 29; and at 70, it’s 1 in 27. Which means that statistically speaking, women are at most risk for breast cancer in their 70s and 80s-but that’s when breast cancer has the highest cure rate because women in that age group usually get a less aggressive and more treatable form of the disease, said Dr. Seewaldt.

9. Chemotherapy isn’t always a given. These days, doctors do genetic profiling on a breast cancer tumor (using advanced tests like the Oncotype DX or MammaPrint) to gauge a woman’s risk of a recurrence. If chances are low, doctors may not advise chemotherapy.

10. Taking certain medications can help. Tamoxifen and raloxifene are drugs that can block estrogen’s ability to promote breast cancer. They lower the chances of developing the disease by about 50 percent in women who carry the BRCA1 or 2 mutation, said Dr. Brown.

11. If it’s caught very early, breast cancer has more than a 90 percent survival rate in the U.S.

12. If you have the BRCA1 or 2 mutations, removing your ovaries lowers your risk by nearly 50 percent.

breast_cancer_awarenessIt’s Breast Cancer Awareness Month. You can help us fight the battle against breast cancer today by purchasing any of the I’m Tired of Breast Cancer bracelet. We give half the sale of every bracelet to Breastcancer.org.

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What women really know about mammogram benefits and risks

Wednesday, August 19th, 2009

mammogramWhat women really know…

Do women fully understand the pros and cons of an annual screening mammogram? Studies suggest they do not.

A 2000 survey of 479 women without a personal history of breast cancer found that only 8% knew that a mammogram could harm a woman (by subjecting her to treatments she didn’t need) and nearly all (94%) did not know that some early-stage breast cancers do not progress.

Likewise, a survey of more than 10,200 Europeans published Aug. 12 in the Journal of the National Cancer Institute found that 92% of the women surveyed dramatically overestimated the ability of mammography to cut cancer deaths or said they didn’t know the magnitude of its benefits.

Here’s how the benefits and risks stack up.

If 1,000 50-year-old women have a yearly mammogram for 10 years:

* One will avoid dying from breast cancer.

* Two to 10 will be treated for a cancer that never would have harmed them.

* Ten to 15 will learn earlier that they have cancer than they would have otherwise, but this earlier diagnosis will not change their prognosis.

* One hundred to 500 will have at least one false alarm.

Source: The Los Angeles Times

Please help us raise money to support the fight against breast cancer by purchasing the I’m Tired of Breast Cancer bracelets. For every bracelet you buy for $10, we give half ($5) to BreastCancer.org.

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Concern Block Party at Paramount Studios Raises $1.3 Million for Cancer Research

Thursday, July 23rd, 2009

block_party_1

What a spectacular night! The Back Lot of Paramount Studios was transformed into a “foodie” fest with tasting stations from 57 of LA’s best restaurants, caterers and beverage companies, including world famous “Pink’s Hotdogs, Lawry’s the Prime Rib and Bistro Gardens,” and the crowd was entertained by Billy Vera and the Beaters, not to mention the 70 plus table casino. More than 3,000 people attended the event and, in this economy, that means that Concern Foundation has a large and loyal following. And, why not? The event raised $1.3 million dollars, which will go to funding 48 cancer researchers nationwide.

The Concern Foundation was conceived in 1968 by a small group of friends in Beverly Hills to channel their grief over a friend’s breast cancer diagnosis. With 95% of net proceeds going directly to research, Concern has funded 554 researchers studying many forms of cancer, primarily in the areas of cancer genetics, cell biology, and immunology. Concern specifically funds researchers who lack financial support for their first major research project. Concern’s impact on the careers of young investigators is profound and helps to sustain the progress made in the cancer research community.

Way to go, Concern!

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Doctor tries to personalize cancer treatment

Tuesday, July 21st, 2009

There is no starched white lab coat for Dr. Laura Esserman. Instead, the tall and striking breast cancer researcher, surgeon and visionary favors colorful clothes, high heels and, on a recent day, metallic blue nail polish.

Before she operates, just as the general anesthetic is being administered, Esserman sings the patient’s requested song. A talented musician with a voice for opera, Esserman delivers songs as varied as “Don’t You Fret” from “Les Miserables” to the Sarah Palin rap from “Saturday Night Live.” Read more…

Source: SFGate

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Drugs Kill Breast Cancer by Halting Tumor’s Ability to Heal Itself

Thursday, June 4th, 2009

An experimental cancer drug made by Sanofi-Aventis SA helped patients with advanced breast tumors live more than 60 percent longer using a new method that stops diseased cells from healing themselves, a new study found.

The treatment, called BSI-201, shrank tumors and slowed new growth in a study of 116 patients with so-called triple- negative breast cancer, an aggressive disease that doesn’t respond to many treatments. Results were presented today at the American Society of Clinical Oncology in Orlando, Florida.

BSI-201 leads an emerging class of treatments known as PARP inhibitors. Most cancer treatments work by blasting DNA with chemotherapy or radiation. Cancer can fight back by using PARP enzymes to fix damaged strands of DNA. The new medicines are designed to block the enzymes and kill the cancer. Read more…

Source: Bloomberg.com

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Breast Cancer: Managing Fear and Anxiety

Friday, April 10th, 2009

breast_cancer_patientBeing diagnosed with breast cancer and going through treatment can cause a flood of different emotions — fears about your long-term survival, anxieties about treatment and side effects, and worries about talking with your children are just some of the things you might experience. All of these feelings are completely legitimate. But how can you stay centered in the midst of so many uncertainties?

The “I’m Tired of Breast Cancer” bracelet supports Breastcancer.org, a nonprofit organization dedicated to providing the most reliable, complete, and up-to-date information about breast cancer. On Wednesday, April 29th, from 8:30pm to 10:00pm EST, Breastcancer.org will be hosting an “Ask-the-Expert Online Conference.” If you or a friend or relative is fighting breast cancer, make sure you’re a part of this online event. Click here for details.

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Wait to schedule breast exams can reach 4 months in New York

Monday, March 30th, 2009

10004868New York women must wait an average of a month for a mammogram - and up to four months in extreme cases, a new study shows.At Wyckoff Heights Medical Center in Brooklyn - the facility found to have the longest wait times - it can take as long as 16-1/2 weeks to schedule the cancer-screening test, according to a survey done by Rep. Anthony Weiner.

“The results are alarming,” said Weiner (D-Brooklyn, Queens), who is pressing to boost the Medicare reimbursement for mammograms in hopes of driving down the wait times.

In the Bronx, women can expect to wait nearly 5-1/2 weeks, according to the survey of 33 mammogram facilities citywide.

In Staten Island, the average lag time between calling for an appointment and getting a scan is just over five weeks.

In Brooklyn and Queens, it can take about four weeks. Read more…

Source: New York Daily News

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Where Are Your Cancer Donations Going?

Wednesday, March 25th, 2009

Thanks to the guidance of their Scientific Review Committee, Concern Foundation has committed nearly $2.5 million dollars (July 2008 - June 2010) in grants to 52 of the best and brightest young cancer researchers throughout the world, focusing on 13 specific cancer research areas.*

Breast Cancer…………………………………………$200,000
Brain Cancer…………………………………………..$100,000
Colon Cancer………………………………………….$100,000
Immunology…………………………………………….$100,000
Leukemia………………………………………………..$200,000
Liver Cancer…………………………………………..$100,000
Lung Cancer……………………………………………$400,000
Lymphoma………………………………………………$200,000
Melanoma……………………………………………….$200,000
Pancreatic Cancer………………………………….$100,000
Prostate Cancer……………………………………..$100,000
Sarcoma………………………………………………….$100,000
Uterine Cancer………………………………………..$100,000
Lautenberg Center Endowment……………….$200,000
Karolinska Institute Endowment………………$300,000

* Full descriptions of each of the Concern funded researchers can be found at www.concernfoundation.org
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Mushrooms, Green Tea May Lower Breast Cancer Risk

Tuesday, March 17th, 2009

mushroomsWomen who get plenty of mushrooms and green tea in their diets may have a lower risk of developing breast cancer, new study findings suggest.The study, of more than 2,000 Chinese women, found that the more fresh and dried mushrooms the women ate, the lower was their breast cancer risk.

The risk was lower still among those who also drank green tea everyday.

It’s known that the rate of breast cancer in China is four- to five- times lower than rates typically seen in developed countries — though the rate has been climbing over the past few decades in the most affluent parts of China.

The current findings suggest that traditional diets — and specifically, large quantities of mushrooms and green tea — may help explain China’s lower breast cancer incidence, according to lead researcher Dr. Min Zhang, of the University of Western Australia in Perth.

She and her colleagues report the findings in the International Journal of Cancer.

The study was conducted in southeast China and involved 1,009 breast cancer patients between the ages of 20 and 87, and an equal number of healthy women the same age. All completed a detailed dietary questionnaire that asked them how often they ate specific foods.

Overall, Zhang’s team found, women who ate the most fresh mushrooms — 10 grams or more per day — were about two thirds less likely to develop breast cancer than non-consumers of mushrooms. Meanwhile, women who ate 4 grams or more of dried mushrooms per day had half the cancer risk of non-consumers.

Finally, mushroom eaters who also drank green tea everyday had only 11 to 18 percent of the breast cancer risk of women who consumed neither.

The study does not prove cause-and-effect, the researchers point out.

They did account for several kinds of risk factors for breast cancer - such as the women’s weight, education level, and exercise frequency and smoking habits — but there could be other factors that explain the findings.

This is also the first study linking high dietary amounts of mushrooms and green tea to lower breast cancer risk, Zhang told Reuters Health.

Therefore, she said, it’s too early for women to assume that the foods will help them avoid the cancer.

Still, it is biologically plausible, the researchers point out.

Lab research has shown that mushroom extracts have anti-tumor properties and, in animals, can stimulate the immune system’s cancer defenses. For its part, green tea contains antioxidant compounds called polyphenols that have been shown to fight breast tumors in animals.

Source: Reuters

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Scientists Say They Have Identified an Enzyme That Helps Cancer Spread Around the Body

Thursday, March 12th, 2009

Cancer metastasis, where the cancer spreads from its original location, is known to be responsible for 90% of cancer-related deaths.

Institute of Cancer Research scientists have found that an enzyme called LOX is crucial in promoting metastasis, Cancer Cell journal reports. Drugs to block this enzyme’s action could keep cancer at bay, they hope.

The researchers studied breast cancer in mice, but are confident that their findings will apply to humans with other cancer types too. Read more…

Source: BBC News

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