Posts Tagged ‘Breast Cancer’

Breast Cancer Awareness - 12 Things You Should Know

Tuesday, October 27th, 2009

breast_cancer_awareness_mothIt’s Breast Cancer Awareness Month, and here’s an article from delmarvanow.com that has 12 things you should know about the disease.

1. Clinical breast exams are as important as mammograms. Mammograms starting at age 40 are crucial (get them earlier if you have a family history of the disease), but they’re an imperfect screening tool, especially in women who have dense breasts. That’s why an annual clinical breast exam from a doctor is a must.

2. Don’t panic if you get called for a mammogram “redo” or have calcifications. Many women over 40 have calcium deposits (calcifications) in their breasts, and most of them are benign.

3. Get your folate. While experts say that an overall healthy diet may help prevent breast cancer, a growing body of research suggests that getting enough of the B vitamin folate (in leafy green vegetables, beans and fortified cereals) may help mitigate the increased risk associated with drinking alcohol.

4. Being overweight is riskiest after menopause. “In postmenopausal women, one of the most significant sources of estrogen comes from body fat,” explained Dr. Isaacs. “So if you’re overweight, you have higher amounts of circulating estrogen, which could stimulate breast cancer growth.” And it doesn’t take much: Losing even 10 pounds may help lower your risk.

5. Active women are less likely to develop and die from breast cancer. Regular exercise has consistently been associated with a lower risk of breast cancer. “Any type of exercise is likely to help by lowering estrogen levels,” Dr. Seewaldt explained.

6. Steer clear of soy supplements. Soy contains isoflavones, which can act like estrogen in your body and potentially stimulate the growth of certain types of breast cancer, explained Seema A. Khan, M.D., a professor of surgery and co-leader of the breast cancer program at Northwestern University in Chicago. But soy foods — edamame, soy milk, tofu — are fine.

7. Lumpy breasts don’t mean a higher risk of cancer. Many women have cysts in their breasts that come and go throughout their menstrual cycles (which are also known as fibrocystic changes). Feeling any kind of lump or bump can be scary, but these types of cysts don’t typically lead to cancer, Dr. Seewaldt points out. Pain also isn’t usually a sign of breast cancer. If you have pain in one or both breasts, rest assured: It’s probably due to hormonal changes, a benign cyst, a ligament strain or another condition, said Dr. Isaacs.

8. Breast cancer risk is not 1 in 8 for all women. That stat applies to lifetime risk, assuming you live to 85 or beyond. At age 40, the average woman has a 1 in 69 chance of getting breast cancer in the next 10 years; at 50, the risk rises to 1 in 42; at 60, it’s 1 in 29; and at 70, it’s 1 in 27. Which means that statistically speaking, women are at most risk for breast cancer in their 70s and 80s-but that’s when breast cancer has the highest cure rate because women in that age group usually get a less aggressive and more treatable form of the disease, said Dr. Seewaldt.

9. Chemotherapy isn’t always a given. These days, doctors do genetic profiling on a breast cancer tumor (using advanced tests like the Oncotype DX or MammaPrint) to gauge a woman’s risk of a recurrence. If chances are low, doctors may not advise chemotherapy.

10. Taking certain medications can help. Tamoxifen and raloxifene are drugs that can block estrogen’s ability to promote breast cancer. They lower the chances of developing the disease by about 50 percent in women who carry the BRCA1 or 2 mutation, said Dr. Brown.

11. If it’s caught very early, breast cancer has more than a 90 percent survival rate in the U.S.

12. If you have the BRCA1 or 2 mutations, removing your ovaries lowers your risk by nearly 50 percent.

breast_cancer_awarenessIt’s Breast Cancer Awareness Month. You can help us fight the battle against breast cancer today by purchasing any of the I’m Tired of Breast Cancer bracelet. We give half the sale of every bracelet to Breastcancer.org.

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Drugs Kill Breast Cancer by Halting Tumor’s Ability to Heal Itself

Thursday, June 4th, 2009

An experimental cancer drug made by Sanofi-Aventis SA helped patients with advanced breast tumors live more than 60 percent longer using a new method that stops diseased cells from healing themselves, a new study found.

The treatment, called BSI-201, shrank tumors and slowed new growth in a study of 116 patients with so-called triple- negative breast cancer, an aggressive disease that doesn’t respond to many treatments. Results were presented today at the American Society of Clinical Oncology in Orlando, Florida.

BSI-201 leads an emerging class of treatments known as PARP inhibitors. Most cancer treatments work by blasting DNA with chemotherapy or radiation. Cancer can fight back by using PARP enzymes to fix damaged strands of DNA. The new medicines are designed to block the enzymes and kill the cancer. Read more…

Source: Bloomberg.com

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Breast Cancer: Managing Fear and Anxiety

Friday, April 10th, 2009

breast_cancer_patientBeing diagnosed with breast cancer and going through treatment can cause a flood of different emotions — fears about your long-term survival, anxieties about treatment and side effects, and worries about talking with your children are just some of the things you might experience. All of these feelings are completely legitimate. But how can you stay centered in the midst of so many uncertainties?

The “I’m Tired of Breast Cancer” bracelet supports Breastcancer.org, a nonprofit organization dedicated to providing the most reliable, complete, and up-to-date information about breast cancer. On Wednesday, April 29th, from 8:30pm to 10:00pm EST, Breastcancer.org will be hosting an “Ask-the-Expert Online Conference.” If you or a friend or relative is fighting breast cancer, make sure you’re a part of this online event. Click here for details.

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Mushrooms, Green Tea May Lower Breast Cancer Risk

Tuesday, March 17th, 2009

mushroomsWomen who get plenty of mushrooms and green tea in their diets may have a lower risk of developing breast cancer, new study findings suggest.The study, of more than 2,000 Chinese women, found that the more fresh and dried mushrooms the women ate, the lower was their breast cancer risk.

The risk was lower still among those who also drank green tea everyday.

It’s known that the rate of breast cancer in China is four- to five- times lower than rates typically seen in developed countries — though the rate has been climbing over the past few decades in the most affluent parts of China.

The current findings suggest that traditional diets — and specifically, large quantities of mushrooms and green tea — may help explain China’s lower breast cancer incidence, according to lead researcher Dr. Min Zhang, of the University of Western Australia in Perth.

She and her colleagues report the findings in the International Journal of Cancer.

The study was conducted in southeast China and involved 1,009 breast cancer patients between the ages of 20 and 87, and an equal number of healthy women the same age. All completed a detailed dietary questionnaire that asked them how often they ate specific foods.

Overall, Zhang’s team found, women who ate the most fresh mushrooms — 10 grams or more per day — were about two thirds less likely to develop breast cancer than non-consumers of mushrooms. Meanwhile, women who ate 4 grams or more of dried mushrooms per day had half the cancer risk of non-consumers.

Finally, mushroom eaters who also drank green tea everyday had only 11 to 18 percent of the breast cancer risk of women who consumed neither.

The study does not prove cause-and-effect, the researchers point out.

They did account for several kinds of risk factors for breast cancer - such as the women’s weight, education level, and exercise frequency and smoking habits — but there could be other factors that explain the findings.

This is also the first study linking high dietary amounts of mushrooms and green tea to lower breast cancer risk, Zhang told Reuters Health.

Therefore, she said, it’s too early for women to assume that the foods will help them avoid the cancer.

Still, it is biologically plausible, the researchers point out.

Lab research has shown that mushroom extracts have anti-tumor properties and, in animals, can stimulate the immune system’s cancer defenses. For its part, green tea contains antioxidant compounds called polyphenols that have been shown to fight breast tumors in animals.

Source: Reuters

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Scientists Say They Have Identified an Enzyme That Helps Cancer Spread Around the Body

Thursday, March 12th, 2009

Cancer metastasis, where the cancer spreads from its original location, is known to be responsible for 90% of cancer-related deaths.

Institute of Cancer Research scientists have found that an enzyme called LOX is crucial in promoting metastasis, Cancer Cell journal reports. Drugs to block this enzyme’s action could keep cancer at bay, they hope.

The researchers studied breast cancer in mice, but are confident that their findings will apply to humans with other cancer types too. Read more…

Source: BBC News

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Enzyme Appears to Suppress Breast Cancer

Tuesday, March 10th, 2009

chip_breast_cancer Scientists in Japan have identified an enzyme which appears to suppress breast cancer. They hope it will spur new therapies to control the second most common cancer in the world. In 2005, it killed 502,000 people worldwide.

In an article published in Nature Cell Biology, the scientists said they injected two kinds of human breast cancer cells into mice. One set carried the CHIP enzyme and the other was without the chemical.

Tumors in the first group of mice with the CHIP enzyme were far smaller than the one without the enzyme, Junn Yanagisawa at the University of Tsukuba’s Graduate School of Life and Environmental Sciences in Japan told Reuters.

The same results were seen in a parallel experiment using a more aggressive line of human breast cancer cells, he added.

“Our conclusion is that we have found that CHIP protein prevents breast tumor growth and metastasis,” Yanagisawa said. Read more…

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INTRODUCING “I’M TIRED OF BREAST CANCER”

Thursday, February 5th, 2009

breast_cancer_borderThere has certainly been a lot of demand for this one and we’re very excited to announce our new “I’m Tired of Breast Cancer” bracelet. This disease is still the second most common cancer in women (behind skin cancer) and the second leading cause of cancer death in women, surpassed only by lung cancer.

Our charity beneficiary for the “I’m Tired of Breast Cancer” bracelet is Breastcancer.org. With over 8 million visitors a year, it is the number one online resource for reliable, complete and up-to-date information about breast health and cancer. Breastcancer.org will receive $5 from each “I’m Tired of Breast Cancer” bracelet sold.

Posted by Carrie Pollare

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