Posts Tagged ‘Diabetes’

Critical Link Between Obesity And Diabetes Discovered

Wednesday, July 8th, 2009

obesityA Monash University study has proven a critical link between obesity and the onset of Type 2 diabetes, a discovery which could lead to the design of a drug to prevent the disease. The findings were published July 8 in the journal Cell Metabolism.

The team, led by Associate Professor Matthew Watt, discovered that fat cells release a novel protein called PEDF (pigment epithelium-derived factor), which triggers a chain of events and interactions that lead to development of Type 2 diabetes.

“When PEDF is released into the bloodstream, it causes the muscle and liver to become desensitised to insulin. The pancreas then produces more insulin to counteract these negative effects, ” Associate Professor Watt said. This insulin release causes the pancreas to become overworked, eventually slowing or stopping insulin release from the pancreas, leading to Type 2 diabetes.”

“Our research was able to show that increasing PEDF not only causes Type 2 diabetes like complications but that blocking PEDF reverses these effects. The body again returned to being insulin-sensitive and therefore did not need excess insulin to remain regulated.” Read more…

Source: Science Daily

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Autism May be Linked to Mom’s Autoimmune Disease

Monday, July 6th, 2009

autismChildren of mothers who have autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and celiac disease have up to a three times greater risk for autism, a new study finds.

Although the association between autism and a maternal history of type 1 diabetes and rheumatoid arthritis had been found in earlier research, the researchers behind the new study say that theirs is the first to find a link between autism and celiac disease. People with celiac disease cannot tolerate gluten, a protein in wheat, rye and barley.

“This finding reinforces the suggestion that autoimmune processes are connected somehow with the cause of autism and autism spectrum disorder,” said researcher William W. Eaton, chairman of the Department of Mental Health at the Bloomberg School of Public Health at Johns Hopkins University. “This finding is on the pathway of finding the cause of autism.”

Eaton noted that there is no clinical significance to the finding but that it could guide future research as scientists try to pin down the cause or causes of autism.

For the study, Eaton’s team collected data on 3,325 Danish children diagnosed with autism spectrum disorder, including 1,089 diagnosed with infantile autism. The children were born between 1993 and 2004, and their data was part of the Danish National Psychiatric Registry. Data on family members with autoimmune diseases came from the Danish National Hospital Register.

The researchers found that children whose mothers had autoimmune disease were at a higher risk of developing autism spectrum disorder than children of mothers who did not have these conditions. In addition, the risk of infantile autism was increased in children with a family history of type 1 diabetes. Read more…

Source: Forbes

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Nick Jonas Lobbies for Diabetes Research

Thursday, June 25th, 2009

nick_jonasThe youngest Jonas brother spent Tuesday lobbying Washington’s power brokers on behalf of diabetes research — starting with the big guy, President Barack Obama.

Clad in a white oxford shirt (no tie) and a gray blazer with the sleeves pushed up, Nick Jonas, 16, stopped by the White House for a photo with the president and children who are living with diabetes.

It was his second time at the White House this year. He and brothers Joe and Kevin hung out there with Obama’s daughters, Malia and Sasha, on the night of Obama’s inauguration.

After the White House, Jonas headed off to Capitol Hill for a private meeting at the office of Sen. Frank Lautenberg, D-N.J.

The teen idol and the senator made small talk about music while photographers snapped their pictures. Roughly a dozen Capitol Hill interns waited quietly across the hall from Lautenberg’s office for a glimpse of Jonas — no loud outbursts or attempts to sneak around security.

“I know some people can become star-struck and lose sight of what they’re here for, but if Nick Jonas makes juvenile diabetes a cause that people are more aware of, it’s worth it,” said Ashley Woolos, an American University student and intern in the office of Rep. Richard Neal, D-Mass. “A younger face might bring younger fans and the fact that juvenile diabetes is not just an older persons’ disease.”

Nick Jonas publicly revealed that he has Type 1 diabetes while performing at a Diabetes Research Institute fundraiser in 2007. He is scheduled to testify on Wednesday before a Senate Homeland Security and Government Affairs Committee hearing on federal funding for diabetes research. Other witnesses include boxer Sugar Ray Leonard and actress Mary Tyler Moore.

The Jonas Bothers created the Change for the Children Foundation, which donates money to charities benefiting children who are disadvantaged or ill. They released their fourth CD, “Lines, Vines, and Trying Times,” last week.

Source: The Associated Press

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Supreme Court Nominee Sotomayor has Type 1 Diabetes

Tuesday, June 2nd, 2009

sotomayorIf confirmed to the U.S. Supreme Court, Sonia Sotomayor would not only be the first Latino to sit on the high court, but also its first known member with Type 1 diabetes.

The Juvenile Diabetes Research Foundation in New York says that the disease shaves an average of seven to 10 years off of a patient’s life, but experts said Wednesday that patients like Sotomayor who manage their disease well can expect to live as long — and work as hard — as healthy Americans.

“There’s absolutely no reason whatsoever that she should be less effective at all,” said Dr. Peter Butler, chief of endocrinology at UCLA Medical Center. “I’m confident she’ll see off most of the other members of the Supreme Court.”

Type 1 diabetes affects an estimated 3 million Americans, who typically are diagnosed during childhood.

When Sotomayor was diagnosed at age 8, in the 1960s, patients with Type 1 diabetes weren’t expected to live full lives. But improvements in monitoring and treatment have changed this outlook. Among the patients who thrive with Type 1 diabetes are five-time Olympic swimming champion Gary Hall Jr. and Chicago Bears quarterback Jay Cutler. Read more…

Posted by Carrie Pollare

Source: Los Angeles Times

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Productivity Impacted by Obesity and Diabetes

Thursday, May 14th, 2009

Obese workers with diabetes are less productive than their normal-weight co-workers, says a U.S. study.

Researchers surveyed 7,338 working adults about missed work time, reduced work effectiveness and impairment of daily activities. The results showed that people who were obese and had type 2 diabetes lost 11 percent to 15 percent of work time (about 5.9 hours a week) because of health problems, compared with 9 percent of work time (about 3.6 hours a week) lost by normal-weight people.

The survey also found that obese people with type 2 diabetes reported impairment during 20 percent to 34 percent of their daily activities, such as taking care of children, shopping and exercising.

The findings are in the May/June issue of the American Journal of Health Promotion. Read more…

Posted by Carrie Pollare

Source: Forbes

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Stem Cell Transplants Help Some Type 1 Diabetics Go Without Insulin

Tuesday, April 28th, 2009

microscopeIn a small experimental study, type 1 diabetics who received stem cell transplants were able to forgo taking insulin for up to four years, according to new research published in the Journal of the American Medical Association.

The study was conducted because an earlier study found that 15 patients with newly diagnosed type 1 diabetes, who underwent stem cell transplants, were able to remain insulin free for an average of 19 months. The new study wanted to test the idea that those effects were simply the result of a “honeymoon period” following the transplant.

In the new study, 12 of 23 patients, ages 13 to 31, remained continuously free from insulin injections for an average of 31 months. Of those, one study participant was insulin free for more than four years, four were insulin free for at least three years, three went without insulin for at least two years, and four achieved this for at least one year. Eight other study participants experienced “transient” insulin independence, meaning they had to start taking insulin again at lower levels.

Richard K. Burt, an associate professor at Northwestern University’s Feinberg School of Medicine in Chicago and co-author of the study, emphasized that stem cell transplants are not without risk. Sterility is one concern, but the most serious risk is a potentially lethal infection, he said. Read more…

Posted by Carrie Pollare

Source: US News & World Report

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Mary Tyler Moore’s New Book Talks about her Struggle with Diabetes

Thursday, April 23rd, 2009

mary_tyler_mooreYou probably either know Mary Tyler Moore as Dick Van Dyke’s wife on the “Dick Van Dyke Show” or as Mary Richards, the spunky, independent single woman form the “Mary Tyler Moore Show.” Both are favorites of mine and she is a wonderful actress, who has also made some incredible movies, like “Ordinary People.”

But, what you may not know is that, around the time of the “Mary Tyler Moore Show,” the actress was diagnosed with type 1 diabetes and now has lost most of her vision because of diabetes-related nerve damage. She is also a strong advocate for diabetes research and education and serves as the international chairwoman of the Juvenile Diabetes Research Foundation, a group she has worked with for years.

In her new book, “Growing Up Again: Lifes, Loves and Oh Yeah, Diabetes,” she offers a personal account of living with diabetes. Though she includes tips and advice from doctors, the book is more a memoir than a how-to for the newly diagnosed. She shares work anecdotes and family tales. The book also includes reflections from others with diabetes and Moore praises the young people she has met for their intelligence and commitment to managing their disease — something she says they do far better than she did in her early years. Read more…

Posted by Carrie Pollare

Source: USA Today

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Doggies Rule! The Story of Hunter, Diva and Diabetes

Monday, April 13th, 2009

This is simply a wonderful story my sister Carrie wrote for the Huffington Post. It’s about two of our favorite things (kids and dogs) and one of our least favorite things (diabetes). We’re determined to help the incredible people at the Diabetes Reaserch Institute find a cure.

diva_1In the middle of the night in a “typical” family home in Florida, a 12 year old girl, named Hunter, sleeps, while her German Shepherd, Diva, lies close by, snoozing on her own bed. All is well with the world…or is it? You see, several times during the night, Diva will get up and check Hunter’s scent. If Diva doesn’t like what she smells, she will alert Hunter’s parents…starting with a nudge, escalating to turning circles or to jumping, whatever it takes to get her job done.

You see, Diva is a diabetes service dog, who has been trained to detect Hunter’s blood sugar levels, because Hunter has type 1 diabetes, a dreadful disease that she has learned to live with since she was diagnosed at just 6 years old. Her daily regimen involves constant testing, insulin shots, even an insulin pump, a very restricted, although incredibly healthy, diet and a lot of help from her beautiful furry companion. And, Diva is amazing at what she does, usually detecting both lows and highs before any symptoms occur. She’s even been known to bring Hunter or her parents a test kit in her mouth if that’s what it takes to get someone’s attention. That’s a blessing because Hunter can get flu-like symptoms, including stomach aches and migraines when her blood sugar is high or headaches and the shakes when it’s low.

Thanks to our work with the Diabetes Research Institute (DRI), our charity beneficiary for the “I’m Tired of Diabetes” bracelet, I was given the pleasure of interviewing Hunter and her mother, Donna, both of whom wear our bracelets, (Diva was there too!) about their struggle with Hunter’s condition and Diva’s role in her treatment. It completely reinforced how important it is to raise money as quickly as possible to find a cure. I had no idea how traumatic it can be and the work involved on the part of both the impacted child and his or her parents to keep the child safe and healthy, both physically and psychologically. Nor did I know that there are service dogs, like the incredible Diva, trained for this type of work.

When Hunter was first diagnosed, the family launched itself into what Donna describes as “Diabetes Academy.” As she tells it, “You spend the first six months living on a computer and getting through a lot of sleepless nights. You have to get up every hour and a half in the middle of the night to test. We couldn’t sleep and Hunter couldn’t get any sleep,” noting that Diva has changed that. We ended up going to a National Children with Diabetes conference and, for three days, we went to school to really learn how to handle the situation.

It was Donna, who came up with the idea of bringing a service dog into the diva_2family. Her rationale was that if police dogs could be trained to pick up the scent of explosives, then dogs should also be able to differentiate someone’s breath and other scents, explaining that diabetics can have a fruity breath smell, a symptom of high blood sugar. “I wasn’t sure if anything like that existed,” she explains. After much research, Donna found that such diabetes service dogs did, in fact, exist in the form of Beverly Swartz and her company, All Purpose Canines, which specializes in placing services dogs with both diabetic and autistic children. The demand for these dogs has been so huge, in fact, that the company has had to stop accepting applications temporarily for diabetic service dogs because of the big wait list and the more rigorous training involved. “Beverly made it very clear that the training took a long time, that there was a lot of care involved with the dogs and that the dog and child had to be matched up if it was going to work,” Donna said.

Nevertheless, they made the trip to South Dakota to meet Diva, who has changed their lives, and ironically, was born on the same day that Hunter was diagnosed. How’s that for “kismet!” “Diva was very quick in catching on to my certain scents,” Hunter said. “When I first saw her, immediately, she was alerting and running all over the place, trying to tell someone that I was ‘high.’” Beverly added that Diva even alerted on the plane on the way back to Florida.

She cautions, however, that a service dog is not right for every family because it takes a lot of work and the right attitude towards the dog. “Out of hundreds of people, maybe three or four are good service dog candidates. The dog isn’t a cure for diabetes. It is another tool,” Beverly asserts. “As good as Diva is, she’s not 100% and she may miss sometimes or give a false hit. But, she’d also rather do her job than eat.” Hunter adds, “She may not be exactly accurate all the time, but she’s pretty darn good…she really is.”

“Hunter knows that if she fails to do her insulin, the dog is going to let her know,” Donna says, “but the emotional support is also paramount in the relationship.” She shared that if Hunter is having a really bad day, where she is experiencing highs or lows, Diva will lie next to her and they’ll put on Neil Diamond music (a family favorite) while she waits for her blood sugar to level out so she starts to feel better.

“Diva is a friend. She’s a companion. She’s like a little sister to me, but in dog form,” Hunter gushes. “No matter how I feel, she comes to me. She knows if I’m mad or something. If I’m sad or having a really bad day, I can just lay there with her and she calms me down and makes me feel better.”

While I was on the phone with Hunter and Donna, Diva started alerting. Donna very calmly said to Hunter, “Diva wants to talk to you. She’s alerting right now. She’s having a fit.” Doggies rule!

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9-Year-Old Diabetes “Spokeskid” Wears his Cause on his Arm!

Wednesday, April 8th, 2009

jakeThis is one of those wow - surprise moments. And, it shows how well our “I’m Tired of…” campaign is taking off through both the hard work of our charity beneficiaries, like Diabetes Research Institute, and the support of those, who wear our bracelets and are helping to spread the word.

Check out this story. A 9-year-old boy, Jake Keith, was diagnosed with type 1 diabetes in July 0f 2006 and has since become a spokesman for those with juvenile diabetes and an ambassador for this year’s Juvenile Diabetes Research Fund Walk. An article on Jake was forwarded to us because the very last paragraph says it all…

“Though the family is taking positive steps to raise money for research and educate others about diabetes, they do get frustrated at times. The words on a bracelet Jake wears sum up his feelings: ‘I’m tired of diabetes.’”

How about that! And, look what’s on his right wrist in the photo above… Read more…

Posted by Carrie Pollare

Source: Frederick News Post

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Type 2 Diabetes More Prevalent in Certain Ethnic Groups

Friday, March 27th, 2009

Recent research results show that type 2 diabetes occurs more in Native Hawaiians, Latinos, African Americans and Japanese Americans than in Caucasians, regardless of their weight.

While doctors said that diabetes is still very much tied to obesity, the statistics were part of a Multiethnic Cohort Study of Diet and Cancer, conducted by the Cancer Research Center of Hawaii in Honolulu. Of approximately 187,000 adults from five ethnic groups who participated, almost 12 percent reported that they had diabetes. The prevalence of diabetes was roughly 16 percent in Native Hawaiians and Latinos, 15 percent in African Americans and 10 percent in Japanese Americans. Only 6% were caucasians. The findings support a role for genetics in the development of type 2 diabetes. Read more…

Posted by Carrie Pollare

Source: Reuters

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